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 It is estimated that 16 to 22 percent of people in the United States may suffer from sleep disorders that may include, most commonly; insomnia, sleep-related breathing disorders (SRBDs), and sleep-related movement disorders. Of the five major categories of SRBDs, central sleep apnea and obstructive sleep apnea (OSA) are most commonly encountered. The most common sleep-related movement disorders include restless legs syndrome, periodic limb movement disorder and sleep bruxism.  

A variety of health issues may be associated with or may underlie a sleep disorder including; headache and/or facial pain, fibromyalgia, stress, anxiety or depression, gastroesophageal reflux disease, central obesity, metabolic abnormalities including type 2 diabetes and metabolic syndrome, high blood pressure and cardiovascular disease.  

From a treatment standpoint; the primary therapy (PAP) for OSA is positive airway pressure (CPAP, BiPAP, APAP).  Positive airway pressure therapy is usually effective if used nightly, i.e. all-night every night, however patient compliance/acceptance can be a significant challenge. Because of this, oral appliance therapy for management of OSA and snoring is recognized as an acceptable treatment option particularly when the patient does not tolerate or will not wear their PAP appliance as necessary to effectively control their OSA.
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